Antibiotic allergy

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Antibiotic Allergy

Although allergic reactions to antibiotics account for only a small proportion of reported adverse drug reactions, they are associated with substantial morbidity and mortality and increased health care costs.1-3 Estimates of the prevalence of antibiotic allergy vary widely.1-3 Any organ may be affected, but the skin is most commonly involved. Data from the Boston Collaborative Drug Surveillance...

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Antibiotic allergy in cystic fibrosis.

Allergic reactions to antibiotics are more common in cystic fibrosis (CF) than in the general population. This in part is due to the improving survival in adults with CF and the increased use of high dose intravenous antibiotics. While some are immediate anaphylaxis type (IgE mediated) reactions, the majority are late onset and may have non-specific features such as rash and fever. Piperacillin...

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OCCASIONAL REVIEW Antibiotic allergy in cystic fibrosis

Allergic reactions to antibiotics are more common in cystic fibrosis (CF) than in the general population. This in part is due to the improving survival in adults with CF and the increased use of high dose intravenous antibiotics. While some are immediate anaphylaxis type (IgE mediated) reactions, the majority are late onset and may have nonspecific features such as rash and fever. Piperacillin ...

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Antibiotic Allergy-clinical Relevance and Consequences

Antibiotic allergy is one of the most commonly encountered problems in clinical practice. The symptoms may range from mildly annoying to life threatening. Drug allergies can become a major problem for patients with the multiple drug allergy syndrome, and more so since the emergence of antibiotic resistant organisms often limits the choice of antibiotics that can be used. β-lactam antibiotics (p...

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Update on the Management of Antibiotic Allergy

Drug allergy to antibiotics may occur in the form of immediate or non-immediate (delayed) hypersensitivity reactions. Immediate reactions are usually IgE-mediated whereas non-immediate hypersensitivity reactions are usually non-IgE or T-cell mediated. The clinical manifestations of antibiotic allergy may be cutaneous, organ-specific (e.g., blood dyscracias, hepatitis, interstitial nephritis), s...

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ژورنال

عنوان ژورنال: The Lancet

سال: 2019

ISSN: 0140-6736

DOI: 10.1016/s0140-6736(18)32218-9